Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-08-05
1992-02-25
Shen, Cecilia
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514409, 546 17, 548411, A61K 31445, A61K 3140, C07D29500
Patent
active
050913875
ABSTRACT:
Disclosed are spirocyclic compounds of the formula: ##STR1## The compounds of formula I are oxytocin antagonists useful in the treatment of preterm labor and dysmenorrhea, and for the stoppage of labor preporatory to Caesarian delivery. Also disclosed are pharmaceutical compositions containing these compounds as well as methods for preparing the compounds.
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Evans Ben E.
Friedinger Roger M.
Pettibone Douglas J.
Caruso Charles M.
Grassler Frank P.
Merck & Co. , Inc.
Parr Richard S.
Shen Cecilia
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