Pharmaceutical composition containing bile acid sequestrant encl

Details Pharmaceutical composition containing bile acid sequestrant encl Pharmaceutical composition containing bile acid sequestrant encl

1990-05-14

1992-02-25

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

424452, 424456, 424457, 424461, 424462, 424460, 424469, 424470, 424473, 424493, 424494, 424495, 424496, 424497, 424501, 424DIG7, 424 7812, 514824, A61K 918, A61K 924, A61K 916, A61K 31785

Patent

active

050911759

ABSTRACT:
A pharmaceutical composition useful for treating hypercholesterolemia comprising a bile acid sequestrant resin such as cholestyramine and cholestipol maintained in a semipermeable water-insoluble material; wherein said semipermeable material enables bile acids from the digest tract to contact and bind to said resin while preventing substances having a higher molecular weight than bile acids from contacting said resin material. A method for treating hypercholesterolemia using the inventive composition is also disclosed.

REFERENCES:
patent: 3974272 (1976-08-01), Polli et al.
patent: 4362711 (1982-12-01), Cerami
patent: 4747881 (1988-05-01), Shaw et al.
patent: 4902501 (1990-02-01), Bandi et al.
Publication titled "Sampling Intestinal Content with a Sequestering Capsule", Mayo Clin Proc, Mar. 1976, vol. 51 by Neville E. Hoffman et al.

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