Fluorinated bile acid derivatives, processes for the preparation

Details Fluorinated bile acid derivatives, processes for the preparation Fluorinated bile acid derivatives, processes for the preparation

1991-09-18

1992-12-29

Cintins, Marianne M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Cyclopentanohydrophenanthrene ring system containing

C07J 900

Patent

active

051753200

ABSTRACT:
Compounds of general formula I ##STR1## wherein R.sub.1 is hydrogen or hydroxy, and the hydroxy group at the 7-position can be either in .alpha. or .beta. configuration, are valuable in human therapy. Compounds I can be prepared by fluorination of the suitably protected 6.alpha.-hydroxy-7-keto-derivatives.

REFERENCES:
patent: 5061701 (1991-10-01), Pellicciari et al.

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