DNA and RNA encoding proteins useful in the regulation of KB-con

Details DNA and RNA encoding proteins useful in the regulation of KB-con DNA and RNA encoding proteins useful in the regulation of KB-con

1993-12-17

1995-10-24

Schwartz, Richard A.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

4351723, 4352523, 43525233, 536 235, C12N 510, C12N 121, C12N 1512

Patent

active

054609658

ABSTRACT:
Proteins, and corresponding DNA and RNA sequences, useful for the regulation of expression of .kappa.B-containing genes are disclosed. These proteins are useful to either stimulate or inhibit the expression of .kappa.B-containing genes. Proteins stimulating the expression of .kappa.B-containing genes have an amino acid sequence at least 80% identical to the amino acid sequence of from position 1 to position 374 of p100 [SEQ ID NO: 2]. Proteins having an inhibitory effect on the expression of .kappa.B-containing genes have sequences either at least 80% identical to the amino acid sequence of from position 407 to the carboxyl end of p100 [SEQ ID NO: 2] or having an amino acid sequence at least 80% identical to the amino sequence of either from position 1 to 100 sor from position 101 to position 374 of p100 [SEQ ID NO: 2].

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