Polymyxin lipopolysaccharide antigen and associated method

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Cyclic peptides

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Details

530387, 424 88, 210691, 502400, 436543, C07K 762, A61K 3900, B01J 2000, G01N 33531

Patent

active

048701580

ABSTRACT:
Antigens that produce antibodies specific for the lipopolysaccharide or endotoxin are produced and characterized. A method of producing the antigen is disclosed. These specific antibodies may be used as immunodiagnostic agents to detect the presence of and quantity of endotoxin in samples.

REFERENCES:
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Dufer et al., "Synthese d'ADN et Synthese d'anticorps dans les cellules spleniques de la Souris apres immunisation, in vivo, par le lipopolysaccharide d'Escherichia coli, modifie par la polymyxine B", Comptes Rendus Hebdom Adai Res Des Sean Ces De L'Academie Des Sciences, Series D vol. 290, pp. 699-701 (1980) and Translation.
Svenson et al., "Immunochemistry Of Salmonella O-Antigens: Preparation of An Octasaccharide-Bovine Serum Albumin Immunogen Representative Of Salmonella Serogroup B O-Antigen And Characterization Of The Antibody Response", J. Immunology 120(5): pp. 1750-1757 (1978).

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