Sterilization of adsorbent and column having improved storabilit

Details Sterilization of adsorbent and column having improved storabilit Sterilization of adsorbent and column having improved storabilit

1985-10-21

1988-05-17

Cintins, Ivars

Liquid purification or separation

Particulate material type separator, e.g., ion exchange or...

B01D 1500

Patent

active

047448997

ABSTRACT:
A process for steam-sterilizing an adsorbent for use in extracorporeal circulation treatment comprising a water-insoluble support and a sulfated polysaccharide immobilized on the support, characterized by sterilizing the adsorbent in an aqueous medium maintainted at pH 5 to 9, whereby the sulfated polysaccharide is prevented from releasing from the support and being deactivated. When the water-insoluble support/sulfated polysaccharide adsorbent is packed in a column with an aqueous buffer solution having a pH 5 to 9 to provide an adsorption column for use in extracorporeal circulation treatment, release and deactivation of the sulfated polysaccharide are prevented and the column can be stored for a long term.

REFERENCES:
patent: 4103685 (1978-08-01), Lupien et al.
patent: 4252653 (1981-02-01), Beck et al.

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