Pharmaceutical vehicle

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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424 19, 424 22, 424 81, 424358, 128271, 424;81, A61K 902, A61K 922, A61K 926, A61K 3178

Patent

active

043449689

ABSTRACT:
Disclosed is a pharmaceutical vehicle comprising (a) a fatty acid glyceride having a melting point higher than 37.degree. C., (b) a water-soluble, low viscous and non-irritating organic substance having a particle size smaller than 28 mesh and a viscosity lower than 300 cps as measured with respect to a 2% aqueous solution, (c) an organic polymeric substance having a particle size smaller than 28 mesh, which is capable of being swollen on contact with water, and (d) a water-soluble surface active agent.

REFERENCES:
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patent: 2696456 (1954-12-01), Hetterick
patent: 2918404 (1959-12-01), Mende et al.
patent: 3440320 (1969-04-01), Sackler
patent: 3776001 (1973-12-01), Hanke
patent: 3875300 (1975-04-01), Homm et al.
patent: 4151274 (1979-04-01), Schlueter et al.
Anschol et al., Chap. 8, "Suppositories", pp. 245-273 in Lachman et al. (ED), The Theory and Practice of Industrial Pharmacy, 2nd Ed., (1976), Lea & Febiger, Phila., Pa.
Chem. Abstr. 92, #220693t (1980) of Jpn. Kokai Tokkyo Kobo 79157820, 13 Dec. 1979, Layered Suppository Base Compositions.
Chem. Abstr. 90, #210156g (1979) of Jpn. Kokai Tokkyo Kobo 7926325, 27 Feb. 1979, Suppositories.
Chem. Abstr. 71, #94739p (1969) of Japan, 69 11, 675, Waxy Compns. for Use as Ointment or Suppositories.

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