Method for inhibiting the growth of cancers

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514449, 424649, A61K 31415, A61K 31335, A61K 3324

Patent

active

059004290

ABSTRACT:
A method for inhibiting the growth of tumors and cancers in mammals comprising administering a chemotherapeutic agent to significantly reduce the tumor in mass and then administering a benzimidazole derivative. Potentiators can also be included in the benzimidazole composition.

REFERENCES:
patent: 3010968 (1961-11-01), Loux
patent: 3669969 (1972-06-01), Lunn
patent: 3738995 (1973-06-01), Adams et al.
patent: 3956262 (1976-05-01), Heyes et al.
patent: 4046906 (1977-09-01), Frensch et al.
patent: 4731366 (1988-03-01), Munro et al.
patent: 4814329 (1989-03-01), Harsanyi et al.
patent: 5098923 (1992-03-01), Karjalainen et al.
patent: 5149527 (1992-09-01), Weisenthal
patent: 5290801 (1994-03-01), Higley et al.
patent: 5310748 (1994-05-01), Wilde et al.
patent: 5329012 (1994-07-01), Anderson
patent: 5364875 (1994-11-01), Wilde
patent: 5629341 (1997-05-01), Camden
patent: 5656615 (1997-08-01), Camden
patent: 5665713 (1997-09-01), Camden
Carter et al., Chemotherapy of Cancer, 2.sup.nd Ed. John Wiley & Sons, N.Y., N.Y. (1981) pp. 362-365.
Derwent Publications, AN 95-400884 and Japan Patent Abstracts, JP 07 277956 (1995).
Teicher et al: "Potentiation of Cytotoxic Therapies by TNP-470 and Minocycline in Mice Bearing EMT-6 Mammary Carcinoma", Breast Cancer Research and Treatment, vol. 36, No. 2, pp. 227-236 (1995).
Bissery et al., "Preclinical Profile Of Docetaxel: Efficacy As A Single Agent And In Combination", Seminars In Oncology; Management Of Breast Cancer: A New Therapeutic Approach, vol. 22, No. 6-S13, 1995 pp. 3-16.
Brown et al J. Am. Chem. Soc. 83, pp. 1764-1765 (1961).
Grenda, et al. J. Org. Chem. 30, 259 (1965).
Georgopapadakov, et al. Science, vol. 264, pp. 371-373 (Apr. 15, 1994).
W.T. Thompson, Agricultural Chemicals Book IV, Fungicides, pp. 154, 121, 123 (1995).
Carter, W.A. CRC Press, Selective Inhibitors of Viral Functions, pp. 277-346 (1975).
Nene. et al., International Science Publisher, Fungicides in Plant Disease Control, Chapter 9, 1993.
Merck Index, Eighth Edition, 1968, p. 1035.
Delatour et al., Therapie, vol. 31, No. 4., pp. 505-515, (1976).
Eigebaly et al. , J. Natl. Cancer Inst., vol. 74, No. 4, pp. 811-815 (1985).
DuPont, Material Safety Data Sheet Benlate Fungicide, Sep. 27, 1994.
Lacey et al., Biochemical Pharma., vol. 34, No. 19, pp. 3603-3605 (1985).
Lacey, Int. J. for Parasitology, 18, (7) pp. 885-936 (1988) Pergamon Press.
Lacey, Biochemical Pharma., vol. 34, No. 7, pp. 1073-1077 (1985).
Chemical Abstracts 113:112365 (1990) Ghannoum et al.,.
Chemical Abstracts 121:175012z, (1994) p. 607,.
Aur, J. Pediatr., 78, No. 1 (1971) pp. 129-131.
Lovett, Diss. Abst. Int. (Sci) vol. 39, No. 11 (1979) pp. 5315-5316.
Lundy et al., Surg. Forum, vol. 27, No. 62 (1976) pp. 132-134.
U.S. application No. 08/680,470, A Pharmaceutical composition for Inhibiting the Growth of Cancers, filed Jul. 15, 1996, Group Art Unit 1614.
U.S. application No. 08/771,193, Pharmaceutical composition for Inhibiting the Growth of Cancers -- Divisional of 08/420,914, filed Dec. 20, 1996, Group Art Unit 1614.
U.S. application No. 08/420,914, A Pharmaceutical composition for Inhibiting the Growth of Cancers, filed Apr. 12, 1995, Group Art Unit 1614 .

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method for inhibiting the growth of cancers does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for inhibiting the growth of cancers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for inhibiting the growth of cancers will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1869693

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.