Method of treating preeclampsia

Details Method of treating preeclampsia Method of treating preeclampsia

1994-05-03

1996-07-09

Gibson, Sharon A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514570, 552310, C07C 5002, A61K 31235

Patent

active

055345484

ABSTRACT:
Straight-chain alkanoic acids, substituted at the .OMEGA.-carbon atom by a substituted phenyl, naphthyl, furyl, or thienyl group and by a substituted 1,4-benzoquinon-2-yl group are effective in the therapy or prophylaxis of conditions associated with lipid peroxide injury to vascular endothelium particularly preeclampsia and eclampsia in pregnant females.

REFERENCES:
patent: 4808627 (1989-02-01), Ogletree
patent: 5015648 (1991-05-01), Humphrey
patent: 5180742 (1993-01-01), Terao et al.
S. W. Walsh et al., Am. J. Obstetrics & Gyn., 169(6):1462-1465 (1993).
Y. Imura, Japanese J. Pharmacol., 52(1):35-43 (1990).
G. Remuzzi, et al., Am. J. Kidney Diseases, 18(3):285-305 (1991).

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