Thiazolinoazetidinones and process therefor

Details Thiazolinoazetidinones and process therefor Thiazolinoazetidinones and process therefor

1979-12-14

1981-06-02

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424270, 544 16, 544 21, C07D27760

Patent

active

042713056

ABSTRACT:
Novel halogenating compounds, derived from triaryl phosphites and chlorine or bromine are employed to convert 7-acylamino-3-hydroxy-3-cephem compounds to 7-acylamino-3-halo-3-cephems and the corresponding C-7 imino halide cephem derivatives. The product 3-halo-3-cephems are antibiotic compounds or intermediates thereto.

REFERENCES:
patent: 3832347 (1974-08-01), Kukolja
patent: 3962227 (1976-06-01), Chauvette
patent: 4077970 (1978-03-01), Foglio et al.
patent: 4079181 (1978-03-01), Tsujii et al.
patent: 4115643 (1978-09-01), Kukolja et al.

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