Cephalosporin derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent

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544 16, 544 22, 544 24, 544 25, 544 26, 544 28, 544 30, C07D 50116

Patent

active

044631731

ABSTRACT:
A compound of the formula I: ##STR1## in which R.sup.1 is any C-3 substituent from antibacterially-active cephalosporins; R.sup.2 is any C-4 substituent from antibacterially-active cephalosporins; R.sup.3 is H, hydroxy, amino, 1-6C alkyl, 1-6C alkanoyl, 1-6C alkoxy, 1-6C alkanoylamino or 1-6C alkylamino, phenyl(1-6C)-alkyl or phenyl, each optionally substituted by methoxy; ##STR2## is of the formula II or III: ##STR3## in which R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8 and R.sup.9 may have a variety of values, e.g. hydrogen, carboxy, cyano or alkyl; and the salts thereof.
Manufacturing processes, pharmaceutical compositions and a method of treating a bacterial infection are also disclosed.

REFERENCES:
patent: 4255424 (1981-03-01), Hannah
patent: 4282219 (1981-08-01), Hannah
patent: 4358447 (1982-11-01), Hannah

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