Bicyclic derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514459, 514460, 549414, A61K 3135, C07D40700

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active

051263653

ABSTRACT:
The invention concerns a bicyclic derivative of the formula I, or a pharmaceutically-acceptable salt thereof, ##STR1## wherein Ar.sup.1 is optionally substituted phenyl or naphthyl; R.sup.1 if (1-6C)alkyl, (3-6C)alkenyl, (3-6C)alkynyl, cyano-(1-4C)alkyl or (2-4C)alkanoyl, or optionally substituted benzoyl; and

REFERENCES:
patent: 2434856 (1948-01-01), La Forge
patent: 3661917 (1972-05-01), Kaiser et al.
patent: 3743737 (1973-07-01), Kaiser et al.
patent: 3795740 (1974-03-01), Baker
patent: 3917597 (1975-11-01), Regnier et al.
patent: 4010267 (1977-03-01), Regnier et al.
patent: 4567184 (1986-01-01), Musser et al.
patent: 4625034 (1986-11-01), Neiss et al.
patent: 4631287 (1986-12-01), Chakraborty et al.
patent: 4725619 (1916-02-01), Chakraborty et al.
patent: 4728668 (1988-03-01), Chakraborty et al.
patent: 4794188 (1988-12-01), Musser et al.
patent: 4839369 (1989-06-01), Youssefyeh et al.
patent: 4876346 (1989-10-01), Musser et al.
patent: 4918081 (1990-04-01), Huang et al.
patent: 4920130 (1990-04-01), Huang et al.
patent: 4920131 (1990-04-01), Huang et al.
patent: 4920132 (1990-04-01), Huang et al.
patent: 4920133 (1990-04-01), Huang et al.
Taylor et al., The Leukotriene Biosynthetic Pathway: A Target for Pharmacological Attack, TIPS, Mar. 1986.
Aharony et al., Kinetic Mechanism of Guinea Pig Neutrophil 5-Lipoxygenase, The Journal of Biological Chemistry, vol. 261, No. 25, pp. 11512-11519, Sep. 5, 1986.
Carey et al., Development and Characterization of a Radioimmunoassay for Leukotriene B.sub.4, 34P, 1986.
Humes et al., Pharmacological Effects of Non-Steroidal Antiflammatory Agents on Prostaglandin and Leukotriene Synthesis in Mouse Peritoneal Macrophages, Biochemical Pharmacology, vol. 32, No. 15, pp. 2319-2322, 1983.
Aked et al., The Inflammatory Response of Rabbit Skin to Topical Arachidonic Acid and Its Pharmacological Modulation, Br. J. Pharmac. (1986) 89, 431-338.
Anderson et al., An In Vivo Model for Measuring Antigen-Induced SRS-A-Mediated Bronchoconstriction and Plasma SRS-A Levels in the Guinea-Pig, Br. J. Pharmac. (1983) 78, 067-074.

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