Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1990-11-19
1992-06-30
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514249, 514250, 514258, 514267, 514293, 514299, 544238, 544250, 544279, 544344, 544350, 546 83, 546122, 546123, A61K 31435, A61K 31495, C07D22100, C07D48702
Patent
active
051263440
ABSTRACT:
The invention concerns pharmaceutically useful novel compounds of the formula I, in which ring B, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, X and Z have the various meanings defined herein, and their non-toxic salts, and pharmaceutical compositions containing them. The novel compounds are of value in treating conditions such as hypertension and congestive heart failure. The invention further concerns processes for the manufacture of the novel compounds and the use of the compounds in medical treatment.
REFERENCES:
patent: 4820843 (1989-04-01), Aldrich et al.
patent: 4880804 (1989-11-01), Carini et al.
Bradbury Robert H.
Luke Richard W. A.
Pearce Robert J.
Roberts David A.
Imperial Chemical Industries plc
Jackson Thomas E.
Raymond Richard L.
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