Process for preparing (3R-(3a.alpha.,4.beta.,7.beta..beta.,7a.al

Details Process for preparing (3R-(3a.alpha.,4.beta.,7.beta..beta.,7a.al Process for preparing (3R-(3a.alpha.,4.beta.,7.beta..beta.,7a.al

1990-12-18

1992-01-28

Ivy, C. Warren

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549458, C07D30793

Patent

active

050845810

ABSTRACT:
Disclosed herein is a novel process in which novel aldehydes ##STR1## and the trans isomer thereof are hydrolyzed by treatment with an alkali metal carbonate, bicarbonate or hydroxide and water to form the cis enantiomer ##STR2## Also disclosed is a process for preparing [1S-[1.alpha., 2.alpha.(Z), 3.alpha., 4.alpha.]]-7-[3[[[[(1-oxoheptyl)amino]acetyl]-amino ]methyl-7-oxabicyclo-[2.2.1]hept-2-yl]-5-heptenoic acid using the above process.

REFERENCES:
patent: 4143054 (1983-03-01), Sprague
patent: 4261904 (1981-04-01), Takeda et al.
patent: 4413054 (1979-03-01), Sprague
patent: 4663336 (1987-05-01), Nakane et al.
patent: 4801607 (1989-01-01), Komoto et al.
G. Guanti et al., Tetrahedron Letters, 27, 4639 (1986).
R. Bloch et al., Tetrahedron Letters, 26, 4087 (1985).
J. Bryan Jones et al., Can. J. Chem. vol. 62, 2578-2582 (1984).
K. P. Lok et al., J. Am. Chem. Soc. 107, 2521-2526 (1985).

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