Synthetic matrix metalloprotease inhibitors and use thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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Details

514357, 514419, 544168, 546334, 548496, A61K 31535, A61K 3140, C07D26528, C07D20732

Patent

active

057734380

ABSTRACT:
Synthetic mammalian matrix metalloprotease inhibitors are disclosed that are useful for treating or preventing diseases wherein said diseases are caused by unwanted mammalian matrix metalloprotease activity and include skin disorders, keratoconus, restenosis, rheumatoid arthritis, wounds, cancer, angiogenesis and shock.

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patent: 4743587 (1988-05-01), Dickens et al.
patent: 4996358 (1991-02-01), Handa et al.
patent: 5304604 (1994-04-01), Davidson et al.
patent: 5453438 (1995-09-01), Campion et al.

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