Glucose responsive insulin secreting .beta.-cell lines and metho

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using tissue cell culture to make a protein or polypeptide

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435 694, 435325, C12P 2100, C12Q 154

Patent

active

057732558

ABSTRACT:
A line of .beta. cells is described which is capable of maintaining high levels of insulin secretion in culture. Such cells are useful in the treatment of diabetes, for example, by encapsulation of the cells in an insulin-permeable membrane device, followed by implantation into a diabetes patient.

REFERENCES:
patent: 4332893 (1982-06-01), Rosenberg
patent: 4477567 (1984-10-01), Healy
patent: 5229365 (1993-07-01), Potter et al.
patent: 5534404 (1996-07-01), Laurance et al.

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