Preparation of therapeutic compounds

Details Preparation of therapeutic compounds Preparation of therapeutic compounds

1978-03-24

1980-02-12

Helfin, Bernard

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

560255, 562460, 562469, 562470, 544176, C07C 6333

Patent

active

041884914

ABSTRACT:
A process is disclosed for preparing arylpropionic acids of formula Ar--CH(CH.sub.3)--COOH, by reacting an aryl Grignard reagent with a metal pyruvate or with a pyruvamide, to form a hydroxy acid of formula Ar--C(OH)(CH.sub.3)--COOH or its amide, and converting the acid or amide to the product.

REFERENCES:
patent: 3385886 (1968-05-01), Nicholson et al.
patent: 3385887 (1968-05-01), Nicholson et al.
patent: 3825553 (1974-07-01), Diamond et al.
patent: 3876800 (1975-04-01), Krausz et al.
patent: 3898269 (1975-08-01), Diamond
patent: 3925458 (1975-12-01), Kogure et al.
patent: 4042617 (1977-08-01), Kogure et al.
patent: 4049823 (1977-09-01), Schacht et al.
Whittingham et al., Chemistry & Industry, p. 159 (1970).
Standen, Kirk-Othmer Encyc. Chem. Tech., 2d Ed., 10, Interscience Publ., N.Y., 721-733 (1966).

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