Pyridinecarboxamide derivatives and process for the preparation

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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546276, 549420, A61K 31455, C07D40112

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active

043328091

ABSTRACT:
N-(5-Tetrazolyl)-6-phenyl-2-pyridinecarboxamide derivatives of the formula: ##STR1## wherein R is hydrogen, a halogen, a lower alkyl or a lower alkoxy, and the phenyl ring A is a phenyl having a substituent selected from the group consisting of amino, a mono(lower)alkylamino, a di(lower)alkylamino, or a lower aliphatic acylamino, and a pharmaceutically acceptable salt thereof, and process for the preparation thereof. Said pyridinecarboxamide derivatives have excellent anti-allergic activities even by oral administration and are useful as an anti-allergic medicine.

REFERENCES:
patent: 3824249 (1974-07-01), Regnier et al.
patent: 4129735 (1978-12-01), Sellstedt et al.

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