Composition of material for osseous repair

Details Composition of material for osseous repair Composition of material for osseous repair

1993-03-04

1995-06-20

Isabella, David

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

Bone

623 66, A61F 228

Patent

active

054257697

ABSTRACT:
An artificial bone substitute composition consisting of fibrous collagen in a calcium sulfate matrix for incorporation in the human body for ultimate replacement by the body in a metabolic turnover and which can be rendered porous by a foaming agent. Such a composition is adaptable for osseous repair by adjusting the collagen and the calcium sulfate in varying ratios to suit particular applications and including admixtures of growth factors. The composition is prepared in a method of formulating a resorbable material by immobilizing a collagen material having mechanical strength characteristics within a calcium sulfate material and subjecting the composition to a hydration reaction which passes through a fluid state to a moldable state and to a solid.

REFERENCES:
patent: 4279812 (1981-07-01), Cioca
patent: 4619655 (1986-10-01), Hanker et al.
patent: 4789732 (1988-12-01), Urist
patent: 4888366 (1989-12-01), Chu et al.
patent: 4904259 (1990-02-01), Itay
patent: 5002583 (1991-03-01), Pitaro et al.

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