Preparation of quinoline derivatives

Details Preparation of quinoline derivatives Preparation of quinoline derivatives

1974-07-05

1976-12-21

Gallagher, Richard J.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260283SY, C07D21520

Patent

active

039988317

ABSTRACT:
A new process for preparing 5-oxo-tetrahydroquinolines comprises condensing a compound of formula II with a ##STR1## compound of formula III to obtain a compound of formula I wherein R, R.sup.1, R.sup.2 and R.sup.3 are selected from hydrogen or alkyl, aralkyl or aryl groups, Y is NH.sub.2 or OH accompanied by an ethylenic bond or Y is oxo and the double bond is absent and A is an amino or lower alkoxy group of 1-4 carbon atoms at least one of Y or A being amino. Compounds of formula I are intermediates for pharmaceuticals.

REFERENCES:
patent: 1806564 (1931-05-01), Prill
patent: 2608557 (1952-08-01), Copenhaver

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