Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1975-06-16
1977-05-17
Rosen, Sam
Drug, bio-affecting and body treating compositions
Lymphokine
195 15, 260112B, A61K 3912, C12K 500, C07G 700
Patent
active
040242439
ABSTRACT:
An improved process for the preparation of hepatitis B antigen by subjecting plasma of hepatitis B donors to isopycanic banding wherein the step gradient is NaBr. Faster and more economical processing is obtained by multiple loading of the step gradient, either NaBr or conventional gradients.
REFERENCES:
patent: 3519400 (1970-07-01), Anderson
patent: 3636191 (1972-01-01), Blumberg et al.
patent: 3838144 (1974-09-01), Leach
Bond et al., The Journal of Infectious Diseases, vol. 125, No. 3, Mar. 1972, p. 263.
McAleer William J.
Wasmuth Edward H.
Behan J. Jerome
Merck & Co. , Inc.
Perrella Donald J.
Rosen Sam
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