Cyclic bridged analogs of .alpha.-MSH and methods thereof

Details Cyclic bridged analogs of .alpha.-MSH and methods thereof Cyclic bridged analogs of .alpha.-MSH and methods thereof

1995-06-06

1997-11-04

Davenport, Avis M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530317, 530312, A61K 3800, A61K 3802, C07K 500, C07K 700

Patent

active

056839812

ABSTRACT:
A novel class of cyclic bridged analogs of .alpha.-MSH are described herein. With the described analogs, when administered in pharmaceutical compositions, it is now possible to achieve normalization of hypopigmentation dysfunctions and to achieve darkening of the skin in the total absence of sun or UV light irradiation.

REFERENCES:
Victor J. Hruby, Life Science, vol. 31, pp. 189-199 No. 3, 1982.
Al-Obeidi et al, J. Med. Chem, vol. 32, pp. 2555-2561, 1989.

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