Method for percutaneously administering physiologically active a

Details Method for percutaneously administering physiologically active a Method for percutaneously administering physiologically active a

1990-09-04

1992-07-07

Stone, Jacqueline

Drug, bio-affecting and body treating compositions

Designated organic nonactive ingredient containing other...

Aftertreated solid synthetic organic polymer

514785, 514947, 514788, A61K 4722, A61K 4714, A61K 4710

Patent

active

051283760

ABSTRACT:
A method of percutaneously administering a physiologically active agent which comprises applying to the skin of a mammal a physiologically active agent in a carrier system which comprises at least one adjuvant, at least one solvent and at least one diol and/or triol moderator. The adjuvant can be selected from aliphatic hydrocarbons, halogen substituted aliphatic hydrocarbons, alcohol esters of aliphatic carboxylic acids, mono- or di-ethers, ketones, higher monoalcohols or mixtures thereof. The solvent can be selected from thioglycerols, lactic acid and esters thereof, cyclic ureas, compounds represented by the general formula R.sub.1 R.sub.2 NCONR.sub.3 R.sub.4, pyrrolidone-type compounds, amides, lactones or mixtures thereof.

REFERENCES:
patent: 4038417 (1977-07-01), Nelson
patent: 4039664 (1977-08-01), Stoughton et al.
patent: 4440777 (1984-04-01), Zupan
patent: 4605670 (1986-08-01), Saito et al.

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