2-amino-1,2,3,4-tetrahydronaphthalene derivatives active on the

Details 2-amino-1,2,3,4-tetrahydronaphthalene derivatives active on the 2-amino-1,2,3,4-tetrahydronaphthalene derivatives active on the

1994-07-28

1995-09-19

Dees, Jose G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514534, 514533, 514547, 514114, A61K 31135

Patent

active

054516080

ABSTRACT:
Derivatives of 2-amino-1,2,3,4-tetrahydronaphthalene and their use in therapeutic field are described.
The compounds are particularly useful in the treatment of arterial hypertension, cardiac decompensation and renal failure, in the treatment of peripheral arteriopathies and in cerebrovascular insufficiency.

REFERENCES:
The Merck Index, An Encyclopedia of Chemicals, Drugs, and Biologicals, 11th Ed., (1989), p. 583.
Haralambos E. Katerinopoulos, et al., "Correlates in Pharmacostructurs", Structure-Activity Relationships for Dopamine Analogs: A Review, vol. 12, No. 3, (1987), pp. 223-248.
Andrew Fitton et al., "Drug Evaluation", Dopexamine hydrochloride: A Review of its Pharmacodynamic and Pharmacokinetic Properties and Therapeutic Potential in Acute Cardiac Insufficiency, Drugs 39, (2) (1990), pp. 308-330.

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