Recombinant soluble epoxide hydrolase

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

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4353201, 43525233, 4352402, 4352551, 536 232, C12N 914, C12N 1555

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054459567

ABSTRACT:
The present invention relates to nucleic acid sequences and methods useful for producing recombinant human soluble epoxide hydrolase (sEH).

REFERENCES:
Beetham et al (1993) Arch Biochem Biophys. 305(1), 197-201.
Maniatis et al (1982) in "Molecular Cloning: A Laboratory Manual" Cold Spring Harbor Laboratory pp. 404-433.
Silva et al (1987) Comp. Biochem Physiol 87B, 95-102.
Dietze et al. (1990) Int J. Biochem. 22, 461-470.
Wixtram et al. (1988) Anal. Biochem 169, 71-80.
Wozney et al. (1990) Meth Enzymol. 182, 738-749.
Arand et al (1991) FEBS Lett. 294, 19-22.
Cameron et al (1989) TIBTECH 7, 66-70.
Skoda et al. (1988) J. Biol Chem 263, 1549-1554.
Preprint, by Drs. Bruce Hammock and David Grant from Dr. Michael Arand. Author/Title: Knehr, Michael, Michael Arand, Thomas Gebel, Hans-Dieter Zeller, Helmut Thomas and Franz Oesch, Isolation and Characterization of a cDNA Encoding Rat Liver Cytosolic Epoxide Hydrolase.
Prestwich, Glenn D. and Bruce D. Hammock, Rapid purification of cytosolic epoxide hydrolase from normal and induced animals by affinity chromatography, Proc. Natl. Acad. Sci. 82:1663-1667 (1985).

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