Base for ophthalmological medicinal preparation on opthalmologic

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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128260, 424 14, 424 16, 424 19, 424 22, 424 32, 424 33, 424 78, 424 81, A61K 922

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active

039782018

ABSTRACT:
A base for ophthalmological medicinal preparations consists of a homopolymer of an amide of acrylic acid having a molecular weight from 30,000 to 1,000,000, and/or a copolymer of an amide of acrylic acid with unsaturated compounds, the molecular weight of the copolymer being from 20,000 to 500,000, and containing from 10 to 90 per cent acrylamide links.
The ophthalmological medicinal film is an oblong plate, 6-9 mm long, 3-5 mm wide and 0.2-0.6 mm thick, of the homopolymer and/or copolymer acrylamide links from 10 to 90 per cent, and an active medicinal ingredient, viz., 3-ethyl-4(1-methyl-5-imidazolyl)-tetrahydrofuran-2-one or atropine, or 3-methoxy-6-sulphanilan idopyridazine, or .beta.-dimethylamino-ethyl-p-butylaminobenzoate, or neamine, or 5-iodo-2-desoxyuridine.
The ophthalmological medicinal film is used for treatment of glaucoma of various forms, thrombosis of the central vein of the retina, atrophy of the optic nerve, for dilating the pupil and paralysis of accommodation in treatment of keratitis, iritis, iridocyclitis, ulcers of the cornea, trachoma, herpetic keratitis, uveitis and adenoviral infections, in extraction of foreign objects from the eye, and in various interventions in the organ of vision.

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patent: 3577516 (1971-05-01), Gould et al.
patent: 3577518 (1971-05-01), Shepherd et al.
patent: 3641237 (1972-02-01), Gould et al.
patent: 3697643 (1972-10-01), Shepherd et al.
patent: 3775537 (1973-11-01), Lehman et al.
patent: 3935303 (1976-01-01), Khromov et al.

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