Cyclic substituted tricyclic quinazolinones

Details Cyclic substituted tricyclic quinazolinones Cyclic substituted tricyclic quinazolinones

1972-11-06

1976-08-31

Todd, G. Thomas

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260244A, 2602564F, 424251, C07D48704

Patent

active

039780597

ABSTRACT:
The compounds are biologically active tricyclic quinazolinones of the class of imidazo[2,1-b]quinazolin-5-ones, pyrimido[2,1-b]quinazolin-6-ones and diazepino[2,1-b]quinazolin-7-ones substituted by a thienyl or furyl group, e.g., 10-(2-thienylmethyl)-2,3-dihydro-imidazo[2,1-b] quinazolin-5(10)-one, and useful, for example, as broncho-dilator agents. Processes for preparation of said compounds include the reaction of a N-carboxy anthranilic anhydride (an isatoic anhydride) with a cyclic pseudothiourea such as 2-organomercapto-4,5-dihydroimidazole or 2-organomercapto-3,4,5,6-tetrahydropyrimidine.

REFERENCES:
patent: 3309369 (1967-03-01), Schindler
patent: 3313815 (1967-04-01), Wolfe et al.
patent: 3379733 (1968-04-01), Houlihan
patent: 3470180 (1969-09-01), Houlihan
patent: 3600390 (1971-08-01), Sherlock

Affiliated with

Also associated with

Rating

Cyclic substituted tricyclic quinazolinones does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cyclic substituted tricyclic quinazolinones, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cyclic substituted tricyclic quinazolinones will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1815240