Hydroisoindolines and hydroisoquinolines as psychotropic

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

548468, A61K 3140, C07D20904

Patent

active

052160181

ABSTRACT:
There are provided nitrogen-containing bicyclic compounds which are useful in the treatment of physiological or drug induced psychosis or dyskinesia in a mammal. These novel compounds are selective sigma receptor antagonists and have a low potential for movement disorder side effects associated with typical antipsychotic agents.

REFERENCES:
Bartman et al., Synth. Commun. 1988, 18:711.
Gray et al., J. Am. Chem. Soc. 1962, 84:89.
Otzenberger et al., J. Org. Chem. 1974, 39:319.
Rehse et al., Arch. Pharm. 1979, 312:982.
Dunet et al., Bull. Soc. Chim. France. 1956, 154:906.
Pogossyan et al., Arm. Khim. Zh. 1980, 33:157.
Rashidyan et al., Arm. Khim. Zh. 1970, 23:474.
Pogossyan et al., Arm. Khim. Zh. 1979, 32:151.
Rashidyan et al., Arm. Khim. Zh. 1968, 21:793.
Grieco et al., J. Chem. Soc. 1987, p. 185.
Larsen et al., J. Am. Chem. Soc. 1986, 108:3512.
Archer et al., J. Med. Chem. 1987, 30:1204.
Deslongchamps et al., Can. J. Chem. 1975, 53:3613.
Jirkovsky et al., Coll. Czech. Chem. Commun. 1964, 29:400.
Meyers et al., J. Org. Chem. 1986, 51:872.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Hydroisoindolines and hydroisoquinolines as psychotropic does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Hydroisoindolines and hydroisoquinolines as psychotropic, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Hydroisoindolines and hydroisoquinolines as psychotropic will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1814879

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.