Human zygin-1

Details Human zygin-1 Human zygin-1

1997-07-31

1999-09-07

Fredman, Jeffrey

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 911, 435 912, 435 9121, 536 231, 536 243, 536 2431, 536 2433, 536 245, C12Q 168, C12P 1934, C07H 2102, C07H 2104

Patent

active

059486198

ABSTRACT:
The invention provides a human zygin-1 (ZY-1H) and polynucleotides which identify and encode ZY-1H. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of ZY-1H.

REFERENCES:
Tessier-Lavigne, M. and C.S. Goodman, "The Molecular Biology of Axon Guidance", Science, 274:1123-1133 (1996).
Reichardt, L.F. and K.J. Tomaselli, "Extracellular Matrix Molecules and Their Receptors: Functions in Neural Development", Annu. Rev. Neurosci., 14:531-570 (1991).
McIntire, S.L. et al., "Genes Necessary for Directed Axonal Elongation or Fasciculation in C. elegans", Neuron, 8:307-322 (1992).
Bloom, L. And H.R. Horvitz, "The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation", Proc.Natl.Acad.Sci.USA 94:3414-3419 (1997). (GI 1927197) (GI 1927198).
Sugita, S. et al., (GI 1778068) GenBank Sequence Database (Accession U63740), National Center for Biotechnology Information: National Library of Medicine, Bethesda, Maryland 20849. (GI 1778069) (1997).
Kuroda, S. et al., (GI 1199670) GenBank Sequence Database (Accession U48249), National Center for Biotechnology Information: National Library of Medicine, Bethesda, Maryland, 20849. (GI 1199671) (1997).
Bloom, L. and H.R.Horvitz, (GI 1927197) GenBank Sequence Database (Accession U60058), National Center for Biotechnology Information: National Library of Medicine, Bethesda, Maryland 20849. (GI 1927198) (1997).
Sugita, S. et al., (GI 1778214) GenBank Sequence Database (Accession U69139), National Center for Biotechnology Information: National Library of Medicine, Bethesda, Maryland 20849. (GI 1778215) (1997).
Bloom, L. and H.R.Horvitz, (GI 1927201) GenBank Sequence Database (Accession U60060), National Center for Biotechnology Information: National Library of Medicine, Bethesda, Maryland 20849. (GI 1927202) (1997).

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