Imidazolyl compounds and their use as medicaments

Details Imidazolyl compounds and their use as medicaments Imidazolyl compounds and their use as medicaments

1985-07-03

1987-05-12

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514397, 514399, 546278, 548335, 548336, C07D40112, C07D23354, A61K 31415

Patent

active

046650806

ABSTRACT:
The present invention relates to new ortho-, meta- and para-substituted imidazolylmethylstyrenes of the formula I ##STR1## and to a process for their preparation. The compounds according to the invention are distinguished by having a specific inhibitory effect on the synthesis of thromboxane, and hence they can be used as medicaments.

REFERENCES:
patent: 4226878 (1980-10-01), Iizuka et al.
patent: 4555516 (1985-11-01), Cross et al.
Fukumori et al., CA 101:396n.
Kaname et al., CA 98:22268u.
Iizuka et al., J. Med. Chem., 1981, 24, 1939-1948.

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