Stable suspension of powder in alcoholic media

Drug – bio-affecting and body treating compositions – Anti-perspirants or perspiration deodorants

Patent

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Other Related Categories

424DIG5, 424 59, 424 67, 424 69, A61K 732, A61K 736

Type

Patent

Status

active

Patent number

046649093

Description

ABSTRACT:
A novel fast drying stable pituitous powder suspension in an alcoholic/aqueous medium having a high alcohol content and a low water content, containing hydroxyethyl cellulose as the essential suspending agent, said alcohol content exceeding the upper solubility of hydroxyethyl cellulose in said alcohol and the water content being sufficient to prevent precipitation of said suspending agent and at least 5% by weight; having utility in the preparation of viscous liquid, semi-solid or solid suspension products such as creams or sticks, more specifically, roll-ons or stick deodorants and medicated lotions which may also be pump activated. The alcohol utilized herein is monohydric such as ethanol, methyl or isopropyl alcohol. However, a polyhydric alcohol such as propylene glycol, glycerine and/or polypropylene glycols may be partially substituted for the monohydric alcohol. Sodium or potassium bicarbonate suspensions have been found to be less irritating to the body and dry faster than bicarbonate solutions because the bicarbonate is delivered as a powder to be activated by body moisture.

REFERENCES:
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patent: 279195 (1883-06-01), Slocomb
patent: 1558405 (1925-10-01), Smith
patent: 2145583 (1939-01-01), Carlson
patent: 2373933 (1945-04-01), Weeks
patent: 2602042 (1952-07-01), Abbott
patent: 3152181 (1964-10-01), Shapiro et al.
patent: 3485915 (1969-12-01), Serstein et al.
patent: 4073880 (1978-02-01), Pader et al.
patent: 4126679 (1978-11-01), Davy et al.
Pharmaceutical Formulas, 1947, vol. II, p. 152.
Martindale, The Extra Pharmacopocia, pp. 1705-1708, 1972.
American Perfumer & Cosmetics, 10/1963, vol. 78, pp. 95-97, Knectel.
Ash, A Formulary of Cosmetic Preparaptions, 1977, pp. 6, 11, 13, 14, 20, 24 and 25.

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