Process for the preparation of tocopherol derivatives and cataly

Details Process for the preparation of tocopherol derivatives and cataly Process for the preparation of tocopherol derivatives and cataly

1995-04-10

1996-07-16

Morris, Patricia L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D31172

Patent

active

055368522

ABSTRACT:
A process is provided for the preparation of an .alpha.-tocopherol derivatives which are useful as antisterile vitamins, hypolipidemics, blood flow increasing agents, anti-cytosenility agents, antioxidants and the like. Catalysts are also provided.
The .alpha.-tocopherol derivatives are represented by the following formula (VII): ##STR1## wherein n stands for 0 or an integer of from 1 to 5. The derivatives can be industrially prepared by employing as catalyst a metal ion-exchanged montmorillonite, metal ion-exchanged bentonite or metal ion-exchanged saponite which is substituted with one metal ion selected from the group consisting of scandium, yttrium, lanthanide element, aluminium, iron, tin, copper, titanium, zinc, nickel, gallium or zirconium.

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