Process for the preparation of o-aminophenyl cyclo-propyl ketone

Details Process for the preparation of o-aminophenyl cyclo-propyl ketone Process for the preparation of o-aminophenyl cyclo-propyl ketone

1993-12-30

1994-11-08

O'Sullivan, Peter

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C07C20974

Patent

active

053629116

ABSTRACT:
There is provided an effective method for the preparation of o-aminophenyl cyclopropyl ketone via the dehydrohalogenation of 1-(o-aminophenyl)-4-halo-1-butanone in the presence of a base and a phase transfer catalyst.

REFERENCES:
patent: 4160784 (1979-07-01), Sugasawa et al.
patent: 4622065 (1986-11-01), Van Gemert
patent: 4769483 (1988-09-01), Lombardi et al.
patent: 5009699 (1991-04-01), Brady et al.
patent: 5107023 (1991-04-01), Brady et al.
George W. Cannon, et al., Organic Syntheses, 1963, Collective vol. 4, pp. 597-600.

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