Chondroitinase attenuated Edwardsiella ictaluri and a vaccine fo

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

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4242351, 424 932, 424 9348, 435245, C12N 121, C12N 136, A61K 3902, A01N 6300

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active

055366589

ABSTRACT:
The present invention provides a chondroitinase attenuated Edwardsiella ictaluri bacteria. Further, this invention provides a vaccine comprising a protective amount of a chondroitinase attenuated strain of Edwardsiella ictduri bacteria and a method for protecting a fish from Enteric Septicemia comprising administering the vaccine to the fish.

REFERENCES:
Cooper III, Dis. Abstract International 52:6223 (Abstract only).
Cooper II, Dissertation, pp. 5 & 6, 31.
Henbert et al Dictionary of Immunology 3rd Ed. p. 4.
Joseph C. Newton et al., "Outer Membrane Protein Profiles of Edwardsiella ictalurifrom Fish," Am J. Vet. Res., (2)51:211-215 (Feb. 1990).
J. C. Newton et al., "Pathology of Experimental Enteric Septicaemia in Channel Fish", Ictalurus punctatus(Rafinesque), Following Immersion-Exposure to Edwardsiella ictaluri, Journal of Fish Diseases, 12:335-347 (1989).
Joseph C. Newton et al., "Isolation, Characterization, and Molecular Cloning of Cryptic Plasmids Isolated from Edwardsiella ictaluri," Am. J. Vet. Res., (11)49:1856-1860 (Nov. 1988).
Clifford E. Starliper et al., "Isozyme Analysis of Edwardsiella ictaluri", Microbios Letters, 37:81-87 (1988).
W. D. Waltman et al., "Biochemical Characteristics of Edwardsiella ictaluri," Applied and Environmental Microbiology(1)51:101-104 (1986).
E. B. Shotts et al., "Pathogenesis of Experimental Edwardsiella ictaluriInfections in Channel Catfish (Ictalurus punctatus)," Can. J. Fish Aquat. Sci. 43:36-42 (1986).
T. Miyazaki et al., "Histopathology of Edwardsiella ictaluriin Channel Catfish, Ictalurus punctatus(Rafinesque)," Journal of Fish Diseases, 8:389-392 (1985).
V. S. Blazer et al., "Pathology Associated with Edwardsiella ictaluriin Catfish Ictalurus punctatusRafinesque, and Danio devario(Hamilton-Buchanan, 1822)," J. Fish Biol.., 27:167-175 (1985).
John P. Hawke et al., "Edwardsiella ictalurisp. nov., the Causative Agent of Enteric Septicemia of Catfish," International Journal of Systematic Bacteriology, (4)31:396-400 (Oct. 1981).

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