Method and compositions for treatment or prevention of pneumocys

Details Method and compositions for treatment or prevention of pneumocys Method and compositions for treatment or prevention of pneumocys

1994-02-04

1995-10-31

Fay, Zohreh

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

514637, A61K 3119, A61K 31155

Patent

active

054629691

ABSTRACT:
The present invention provides methods for treating and preventing the onset of Pneumocytis carinii pneumonia (PCP) comprising administering to a mammal in need of such treatment or prevention an effective amount of a pharmaceutically acceptable iron chelator. This invention also provides a method for treating or preventing the onset of PCP comprising administering to a mammal in need of such treatment or prevention a composition comprising the following components: (a) a pharmaceutically acceptable iron chelator; (b) a compound selected from trimethoprim/sulfamethoxazole and pentamidine; and (c) a pharmaceutically compatible carrier or diluent, wherein the amounts of said component (a) and said component (b) in combination are effective in treating said pneumonia. Also provided is a composition for the treatment or prevention of PCP.

REFERENCES:
patent: 2410796 (1986-11-01), Newberry et al.
patent: 3049544 (1962-08-01), Stenbuck et al.
patent: 3341541 (1967-09-01), Hoffer
patent: 4419365 (1983-12-01), McLachlan
patent: 4614797 (1986-11-01), Nagata et al.
Allegra et al., (1987), New England Journal of Medicine, 317:978-985.
Boelaert et al., (1991), Am. J. Kidney Dis., 18:660-667.
Carotenuto et al., (1986), J. of Immunol., 136:2342-2347.
Chiu et al., (1986), Brit. Med. J., 292:97.
Clarkson et al., (1988), Antimicrobial Agents and Chemotherapy, 32:1158-1163.
Daly et al., (1989), Am. J. Med., 87:468-471.
Edman et al., (1988), Nature, 334:519-522.
Fritsch et al., (1985), Exp. Parisitol, 60:171-174.
Gallacher et al., (1989), Critical Care Medicine, 17:104-105.
Gallant et al., (1986), New Eng. J. Med., 341 [25]:1653.
Graziano et al., (1978), J. Ped., 92(4):648-652.
Green et al., (1988), British Journal of Clinical Pharmacology, 487-491.
Haverkos, (1984), Am. J. Med., 76:501-508.
Hughes, (1987), N. Eng. J. Med., 317:1021-1023.
Hynes, (1970), J. Med. Chem., 13:1235-1237.
Jones et al., (1983), Eur. J. Clin. Microbiol., 2:411-413.
Jones et al., (1987), Nature, 267:63-64.
Kouides et al., (1988), Brit. J. Haematol., 70:382-383.
Kovacs et al., (1988), Journal of Infectious Diseases, 158:254-259.
Lederman et al., (1984), Blood, 64:748-753.
Lowy et al., (1984), Animicrob. Agents Chemotherap. 25 [3.
Masawe et al., (1974), Lancet, 2:314-317.
Mazzoleni et al., (1991), Diges. Dis. and Sci., 36:1155-1160.
Peto et al., (1986), Br. J. Haematol., 63:273-280.
Pollack et al., (1987), Proc. Soc. Exp. Biol. Med., 184:162-164.
Queener et al., (1987), Antimicrobial Agents and Chemotherapy, 31:1323-1327.
Queener et al., (1988), Antimicrobial Agents and Chemotherapy, 32:807-813.
Raventos-Suraez et al., (1982), Am. J. Trop. Med. Hvg., 3(5):919-922.
Schafer et al., (1985), Arch. Intern. Med., 145:1217-1221.
Sattler et al., (1988), Annals of Internal Medicine, 109:208-287.
Vandenbergh et al., (1983), App. and Environ. Micro., 46 [.
Weinberg et al., (1986), Blood, 68:286A.
Youdim, Am. Rev. Resp. Dis., 99:925-931 (Abstract only) (1969).

Affiliated with

Also associated with

Rating

Method and compositions for treatment or prevention of pneumocys does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method and compositions for treatment or prevention of pneumocys, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and compositions for treatment or prevention of pneumocys will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1772738