Method of treatment to inhibit metastasis

Details Method of treatment to inhibit metastasis Method of treatment to inhibit metastasis

1983-03-01

1986-05-13

Rosen, Sam

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

A61K 3562

Patent

active

045885877

ABSTRACT:
Method for treating a patient to inhibit metastasis of malignant cells by administering to the patient a therapeutically effective amount of a composition including a blood anticoagulant and a protease inhibitor. A composition apparently unique for this purpose is a leech salivary gland extract, the anticoagulant effect and protease inhibitory effect of which are believed to be significant. Other significant components may also be present in the leech salivary gland extract and these components may act synergistically in producing the observed antimetastatic effect.

REFERENCES:
Gasic et al.,-Cancer Research, vol. 43, Apr. 1983, pp. 1633-1636.
Budzynski et al.-PSEBM, vol. 168, (1981), pp. 259 & 261-265.

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