Process for the production of 2-cyanoiminothiazolidine

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D27718

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055918590

ABSTRACT:
A process for the production of 2-cyanoiminothiazolidine by reaction of 2-aminoethanethiol (cysteamine) with a dialkyl-N-cyanoimidocarbonate.

REFERENCES:
patent: 5532258 (1996-07-01), Katsura et al.
Org. Prep. Proced. Ind., Bd. 23, Nr. 6, 1991, pp. 721-728, XP002002935 Zmitek, J. et al.: "The Synthesis and Reactions of N-Cayno-O-methylpseudoureas" *Beispiel 7A*.
J. Heterocycl. Chem., Bd. 24, Nr. 1, 1987, pp. 275-278, XP002002936 Webb, R., W. Et Al.: "Diphenyl Cayncarbonimidate and Dichlorodiphenoxymethane as Synthones for the Construction of Heterocyclic Systems of Medical Interest".
J. Med. Chem., Bd. 38, No. 17, 1995, pp. 3236-3245, XP002002937 Atwal, K., S. et al.: "Cardioselective Anti-Ischemic ATP-Sensitive Potassium Chanel Openers. 3. Stucuture-Activity Studies on Benzopyranyl Cyanoguanidines: Modification of the Cyanoguanidine Portion".

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