Parvovirus empty capsids

Details Parvovirus empty capsids Parvovirus empty capsids

1991-02-15

1999-05-18

Crouch, Deborah

Chemistry: molecular biology and microbiology

Vector, per se

4352351, 435325, 435455, C12N15/00;7/00;5/00

Patent

active

059050403

ABSTRACT:
Empty viral capsids, particularly animal parvoviral empty capsids, induce protective antibody response against the virus. The empty viral capsids are obtained by recombinant DNA techniques. Expression vectors are constructed containing structural genes encoding capsid proteins in self assembling form. Eukaryotic transfectants express self-assembled empty viral capsids which can be used to vaccinate against the virus or antigenically related species of the virus.

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