Process for preparing 2-chloro-4-fluorophenol

Details Process for preparing 2-chloro-4-fluorophenol Process for preparing 2-chloro-4-fluorophenol

1990-09-06

1991-10-01

Lone, Werren B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Oxygen containing

568779, C07C 3927, C07C 3762

Patent

active

050535579

ABSTRACT:
A process is disclosed for preparing 2-chloro-4-fluorophenol which comprises chlorinating 4-fluorophenol with a chlorinating agent in the presence of water. The process according to the present invention has advantages in that the chlorination can be carried out using inexpensive reagents without requiring the use of particular apparatus and under mild conditions, and the desired product can be obtained in good yields and with high selectivity. 2-Chloro-4-fluorophenol obtained in the present invention is useful as a starting material for producing various pharmaceutical agents and agricultural agents.

REFERENCES:
patent: 3929907 (1975-12-01), Janzon et al.
patent: 4620042 (1986-10-01), Kawai et al.

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