Orally administrable anti-metastatic lectin compositions and met

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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4241951, 530396, A01N 3718, A61K 3702, A61K 3578

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active

050533860

ABSTRACT:
Compositions and methods of treatment comprising the lectins Abrin and Abrus agglutinin for the suppression of post-surgical malignant tumor metastasis are disclosed. Also disclosed is the administration of compositions and methods of treatment utilizing the above lectins in combination with either or both radiation treatment and/or chemotherapy.

REFERENCES:
Dyer "An Index of Tumor Chemotherapy" National Cancer Institute, NIH, Mar. 1949, p. 175.
Chabner, et al. "Clinical Pharmacology of Cancer Chemotherapy" taken from Chapter 9 of Cancer, Principles and Practice of Oncology, Lippincott Co., Philadelphia, 1982, pp. 158-159.
Tung, T. C. et al., J. Chinese Oncol. Soc., 3(3) 1-8 (1987), Inhibitory Effect by Orally Administered Abrus Agglutinin on the Anti-Metastasis of Sarcoma-180 and B-16 Melanoma.

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