Process for producing R(-)-mandelic acid and derivatives thereof

Details Process for producing R(-)-mandelic acid and derivatives thereof Process for producing R(-)-mandelic acid and derivatives thereof

1991-03-29

1993-06-29

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing nitrogen-containing organic compound

435130, 435146, 435280, 435822, 435829, 435839, 435840, 435872, 435874, C12P 742, C12P 1300, C12P 4100, C12P 1100

Patent

active

052234169

ABSTRACT:
A process for the predominantly producing R(-)-mandelic acid or a derivative thereof which comprises subjecting (i) R,S-mandelonitrile or a derivative thereof, or (ii) a mixture of prussic acid and benzaldehyde or a derivative of benzaldehyde to the action of a microorganism selected from the group consisting of the genus Aureobacterium, Pseudomonas, Caseobacter, Alcaligenes, Acinetobacter, Brevibacterium, Nocardia, and Bacillus or treated cells thereof, which the microorganism is capable of stereospecifically hydrolyzing a nitrile group of the R,S-mandelonitrile or a derivative thereof, in a neutral or basic aqueous reaction system to produce the R(-)-mandelic acid.

REFERENCES:
Derwent Abs. 88-303602/43 Idemitsu Kosan KK J63222696 (Sep. 1988).
Hiromichi Ohta et al., "Microbial Hydrolysis of Substituted . . . Ethanolamines", Agricultural and Biological Chemistry, vol. 53, No. 1, Jan. 1989, Tokyo, Japan, pp. 281-283.
World Patents Index Latest, Week 9203, Derwent Publications Ltd., London, GB; AN 92-029694 & JP-A-3 277 292 (Aishi Chemical) Dec. 9, 1991.

Affiliated with

Also associated with

Rating

Process for producing R(-)-mandelic acid and derivatives thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for producing R(-)-mandelic acid and derivatives thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for producing R(-)-mandelic acid and derivatives thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1754704