Negatively charged specific affinity reagents

Details Negatively charged specific affinity reagents Negatively charged specific affinity reagents

1992-02-21

1993-06-29

Reamer, James H.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

424 2, 424 9, 424486, 424400, A61K 4300

Patent

active

052232425

ABSTRACT:
An in vivo imaging or therapeutic method including administering to a mammal a specific affinity reagent including a physiologically compatible polymer bonded to one or more specific affinity molecules capable of selectively binding to a predetermined substance or class of cells, and one or more reporter groups capable of providing detectable contrast between the predetermined substance or class of cells and cells or substances of the mammal to which the specific affinity reagent does not bind, or of killing cells of the predetermined class.

REFERENCES:
patent: 4046722 (1977-09-01), Rowland
patent: 4731239 (1988-03-01), Gordon

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