N-thiazolymethylthioalkyl-N'-alkylamidines and related compounds

Details N-thiazolymethylthioalkyl-N'-alkylamidines and related compounds N-thiazolymethylthioalkyl-N'-alkylamidines and related compounds

1988-05-03

1990-02-27

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

A61K 31425

Patent

active

049047922

ABSTRACT:
N-alkyl-N'-(2-aminomethyl-4-thiazolylmethylthio)alkyl guanidines, thioureas, ethenediamines and related compounds, H.sub.2 -receptor antagonists, useful in inhibiting gastric acid secretion in mammals.

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Mar., Advanced Organic Chemistry: Reactions, Mechanisms, and Structure, pp. 294 and 745 (1968).
Street et al., Scand. J. Gastroenterol, 19 (Supp. 101), 109 (1984).

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