Process for the preparation of .alpha.-aryl and .alpha.-heteroar

Details Process for the preparation of .alpha.-aryl and .alpha.-heteroar Process for the preparation of .alpha.-aryl and .alpha.-heteroar

1986-07-07

1988-09-20

Higel, Floyd D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

534558, 534885, 534886, 546 14, 546342, 548110, 548146, 548214, 549 4, 549 76, 549 78, 549491, 549498, 556400, 556482, 556486, 560 35, 560168, 568308, 568309, 568322, 568325, 568331, 568332, 568335, 260405, C07C 4500, C07C 4752, C07C21350, C07C30746, C07C33322

Patent

active

047727144

ABSTRACT:
Disclosed is a process for the preparation of alpha-aryl and alpha-heteroaryl ketones useful as intermediates in the synthesis of various pharmaceutical and agricultural chemicals, which process operates according to the following reaction scheme: ##STR1##

REFERENCES:
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Chemical Abstract 87: 167732y (1977), German Offen. No. 2,659,580.
Merck Index, 10th Edition, No. 5673.
H. H. Hatt, A. Pilgrim, W. J. Hurrah, J. Chem. Soc., 93 (1936).
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Theodore W. Evans, William M. Dehn, J. Am. Chem. Soc., 52,252 (1930).
The Pharmacological Basis of Therapeutics, 7th Edition, McMillen, 1985.
Sakakura et al, J. Chem. Soc. (London), Chem. Commun., volume of 1985, No. 21, pp. 1545 to 1546.
Kitazume et al, Bull. Chem. Soc., Jpn., vol. 53, pp. 2064 to 2066 (1980).
Theilheimer, "Synthetic Methods of Organic Chemistry", vol. 36, p. 335, No. 781 (1982).

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