Purification of urokinase

Details Purification of urokinase Purification of urokinase

1978-03-06

1979-04-03

Hart, Charles N.

Textiles: fiber preparation

195 62, 210 24, C07G 7026

Patent

active

041475925

ABSTRACT:
A process for purifying urokinase which comprises contacting a crude aqueous solution of urokinase with an ionic pullulan gel and thereafter separating and recovering an aqueous solution of urokinase devoid of harmful impurities.

REFERENCES:
patent: 2983647 (1961-05-01), Kjeldgaard et al.
patent: 3256158 (1966-06-01), White
patent: 3723252 (1973-03-01), Ogawa et al.
patent: 3957582 (1976-05-01), Stried et al.
patent: 4010074 (1977-03-01), Vemura et al.
patent: 4066506 (1978-01-01), Johnson et al.
Sgouris et al., "The Purification, Assay, Sterilization, and Removal of Pyrogenicity of Human Urokinase", in Vox Sanguinis, vol. 7, pp. 739-749 (1962).

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