Wound headling composition of TGF-alpha and PDGF

Details Wound headling composition of TGF-alpha and PDGF Wound headling composition of TGF-alpha and PDGF

1987-12-22

1989-10-17

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

424101, 514 2, 514 12, 530399, 530380, A61K 3736

Patent

active

048747467

ABSTRACT:
Healing an external wound or regenerating bone of a mammal by administering to the mammal a composition containing purified platelet-derived growth factor and purified transforming growth factor alpha.

REFERENCES:
patent: 4742003 (1988-05-01), Derynck et al.
Science, 235:350-352 (1987), Schultz et al.
Proc. Acad. Sci. USA, 84: 7696-7700 (1987), Lynch et al.
J. Trauma 24, No. 9, 549-552 (1984), Grotendorst.
J. Clin. Invest. 76, Dec., 1985, 2323-2329, Grotendorst et al.
Science, 219, 1329-1331 (1983), Sporn et al.
Chem. Abst. 106 (1987), 96915h, Schultz et al.
Sporn et al., U.S. Ser. No. 468,590, filed Feb. 22, 1983.

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