Inhibiting xanthine oxidase with 3-haloalkyl substituted benzoth

Details Inhibiting xanthine oxidase with 3-haloalkyl substituted benzoth Inhibiting xanthine oxidase with 3-haloalkyl substituted benzoth

1972-05-24

1976-07-13

Meyers, Albert T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

A61k 1902

Patent

active

039695182

ABSTRACT:
Method for decreasing the concentration of uric acid in the blood and urine of a mammal by the administration of a 3-haloalkyl-1,2,4-benzothiadiazine-1,1-dioxide product or 3,4-dihydro derivative thereof. The products employed in this method of treatment are prepared by conventional methods employing the appropriate orthanilamide and haloalkanoic acid halide or carboxaldehyde. The products effect the lowering of the uric acid level by virtue of their xanthine oxidase inhibiting properties.

REFERENCES:
patent: 3137625 (1964-06-01), Biel
patent: 3288678 (1966-11-01), DE Stevens et al.
patent: 3443004 (1969-05-01), Lachman et al.
patent: 3499082 (1970-03-01), DE Stevens et al.
patent: 3504089 (1970-03-01), Robison
Novello et al., Ind. Chim. Belge 1967, 32 (Spec. No.) 222-225.

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