Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1982-05-20
1983-03-08
Rizzo, Nicholas S.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424270, 424271, C07D49900, A61K 3143
Patent
active
043760767
ABSTRACT:
Bis-Esters of 1,1-alkanediols with 6-beta(hydroxymethyl)penicillanic acid 1,1-dioxide and 6-betaacylaminopenicillanic acids are useful as antibacterial agents. Intermediates useful for the preparation of these compounds include halomethyl, alkylsulfonyloxymethyl and arylsulfonyloxymethylesters of 6-beta(hydroxymethyl)penicillanic acid 1,1-dioxide and 6-beta-aminopenicillanoyloxymethyl-6'-beta-(hydroxymethyl)penicillanate 1,1-dioxide.
REFERENCES:
patent: 4244951 (1981-01-01), Bigham
patent: 4309347 (1982-01-01), Bigham
Blackwood Robert K.
Frost Albert E.
Knuth Charles J.
Pfizer Inc.
Rizzo Nicholas S.
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