Substituted acyl derivatives of octahydro-1H-isoindole-1-carboxy

Details Substituted acyl derivatives of octahydro-1H-isoindole-1-carboxy Substituted acyl derivatives of octahydro-1H-isoindole-1-carboxy

1982-06-14

1985-03-05

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

2601125R, 548512, 548515, 548470, 548472, 514416, A61K 3700, C07C10352

Patent

active

045030430

ABSTRACT:
Substituted acyl derivatives of octahydro-1H-isoindole-1-carboxylic acid compounds and the pharmaceutically acceptable salts thereof are produced by acylating a suitably substituted octahydro-1H-isoindole with a suitably activated substituted carboxylic acid and when desired hydrolyzing the resulting product. The compounds of the invention, their salts and pharmaceutical compositions thereof are useful as antihypertensive agents.

REFERENCES:
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patent: 4404206 (1983-09-01), Vincent et al.
Derwent Abstract of Belgium Patent 873,092, Published, Jun. 1979.
Derwent Abstract of Germany Patent 2,720,996, Published, Nov. 1977.
Derwent Abstract of Belgium Patent 871,574, Published, Apr. 1979.
European Patent Publication No. 50-800 filed Oct. 15, 1981, published May 5, 1982, (Claiming Priority from U.S. Ser. No. 199,886 and U.S. Ser. No. 258,484).

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