Stereoselective preparation of 3-substituted-4-piperidine compou

Details Stereoselective preparation of 3-substituted-4-piperidine compou Stereoselective preparation of 3-substituted-4-piperidine compou

1987-11-02

1989-07-18

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546194, 546210, 546211, 546213, 546223, C07D41706

Patent

active

048495212

ABSTRACT:
The present invention is directed to an improved stereoselective tandem substitution and reduction of an imine precursor to the cis form of 3-substituted-4-(phenylanilo)piperidine compounds or their substituted derivatives.

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D. B. Collum et al., "Substituent Effects on the Stereochemistry, etc", 2/13/84, 4 pgs., J. Am. Chem. Soc. 106, (4865-4869).
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